Star Trek II: The Wrath of Khan was arguably the best of the Star Trek movies focusing on the cast of the original series. The most famous scene is, I think, the conversation between Khan and Admiral Kirk after Kirk finds himself marooned on the Regula planetoid with no way to escape.
Comic book artist Bruce McCorkindale offers this mashup of that scene showing the Shatneresque Muppet Link Hogthrob and, in the role of Khan Noonien Singh, Pepe the King Prawn.
McCorkindale is fond of Muppet movie mashups. You can see more on his Instagram page, including those for Doctor Strangelove, Kenneth Branagh’s Hamlet, and M*A*S*H.
-via Josh Hadro